Anticancer and Antiviral Activity of Chlorine Dioxide by Its Induction of the Reactive Oxygen Species --
"The results of this study indicate that chlorine dioxide possesses anticancer and antiviral activities probably due to its
inducing activity of reactive oxygen species (ROS) production."
European Patent: EP1955719B1 /
Chlorine Dioxide Gas for Use in Treating Respiratory Virus Infection -- "The present invention relates
to chlorine dioxide for use in treating respiratory virus infection." Mention made of use in treating H1N1 which is a
coronavirus type.
Evaluation of the antiviral activity of chlorine dioxide and sodium hypochlorite against feline calicivirus, human influenza
virus, measles virus, canine distemper virus, human herpesvirus, human adenovirus, canine adenovirus and canine parvovirus. --
"We evaluated the antiviral activity of a chlorine dioxide gas solution (CD) and sodium hypochlorite (SH) against feline
calicivirus, human influenza virus, measles virus, canine distemper virus, human herpesvirus, human adenovirus, canine adenovirus
and canine parvovirus. CD at concentrations ranging from 1 to 100 ppm produced potent antiviral activity, inactivating
>or= 99.9% of the viruses with a 15 sec treatment for sensitization. The antiviral activity of CD was approximately 10 times
higher than that of SH."
Antiviral Effect of Chlorine Dioxide against Influenza Virus and Its Application
for Infection Control -- " We review current information based on the efficiency of ClO 2 solution and gas,
and also discuss the application of ClO 2 against influenza pandemics outbreak."
Chlorine Dioxide (CLO2) As a Non-Toxic Antimicrobial Agent for Virus, Bacteria and Yeast
(Candida Albicans) -- "Explanation of the biochemical mechanisms of acid of CLO2 as an antimicrobial agent,
is presented. Particular attention is given to Candida albicans, cytomegalovirus, polio virus, Herpes I and II, HTLV-III and
Pseudomonas responding to the clinical application of CLO2."
Inactivation of Airborne Bacteria and Viruses Using Extremely Low Concentrations of Chlorine Dioxide Gas. --
"Here, we demonstrate that chlorine dioxide (ClO2) gas at extremely low concentrations, which has no detrimental effects
on human health, elicits a strong effect to inactivate bacteria and viruses and significantly reduces the number of viable
airborne microbes."
Can chlorine dioxide prevent the spreading of coronavirus or other viral infections? Medical hypotheses --
Conclusion: In this editorial, we summarized the unique properties of chlorine dioxide, which make it an
ideal and nonspecific antimicrobial agent at concentrations harmless to humans, and we reviewed previous research on preventing
viral infections with gaseous ClO2. Based on this background, we suggested some novel hypothetical methods using chlorine dioxide
to disinfect rooms, prevent human infection, and slow down viral spread. These are nonspecific methods, which could be used against
any newfound virus as a first line of protection until effective specific countermeasures are developed.
Degradation of the Poliovirus 1 genome by chlorine dioxide -- "This study was undertaken to gain an
understanding of the factors that influence viral RNA degradation in the presence of chlorine dioxide (ClO(2)."
Inactivation of Poliovirus with Chlorine Dioxide.
Inactivation of human and simian Rotaviruses by chlorine dioxide -- The inactivation of single-particle
stocks of human (type 2, Wa) and simian (SA-11) rotaviruses by chlorine dioxide was investigated.
Evaluation of gaseous chlorine dioxide for the inactivation of Tulane virus on
blueberries -- To determine the effectiveness of gaseous chlorine dioxide (gClO2) against a human norovirus surrogate
on produce.
Mechanisms of inactivation of hepatitis A virus in water by chlorine dioxide --
In this study, to elucidate the mechanisms of inactivation of hepatitis A virus (HAV) by chlorine dioxide, cell culture,
enzyme-linked immunosorbent assay (ELISA), and long-overlapping RT-PCR were used to detect the infectivity, antigenicity, and
entire genome of HAV before and after disinfection. The results revealed the complete inactivation of infectivity after a
10-min exposure to 7.5mg of chlorine dioxide per liter.
The Ability of Two Chlorine Dioxide Chemistries to Inactivate Human Papillomavirus-contaminated
Endocavitary Ultrasound Probes and Nasendoscopes -- For the first time, two chlorine dioxide chemistries are tested
and shown to be efficacious in killing HPV. This study tested drying the infectious virus directly onto endocavitary ultrasound
probes and nasendoscopes, therefore validating a more realistic system to demonstrate disinfectant efficacy.
Efficacy and Safety Evaluation of a Chlorine Dioxide Solution -- This study is noteworthy,
since it uses a chlorine dioxide solution (UC-1) with the same concentration level as
Biodox: 2,000 ppm of gaseous
chlorine dioxide.
Growth Inhibitory Effects of Chlorine Dioxide on Bacteria --
"This study will provide fundamental data to research growth inhibition by ClO2 gas with bacteria of clinical importance value."
Chlorine dioxide (ClO2) -- This chapter discusses the characteristics and generation of ClO2,
the basis of its antimicrobial action, and its antimicrobial effects on the safety and quality of produce.
Growth Inhibitory Effects of Chlorine Dioxide on Bacteria -- (complete study) -- This study will provide
fundamental data to research growth inhibition by ClO2 gas with bacteria of clinical importance value.
Efficacy of chlorine dioxide mouthwash against halitosis -- Gargling with mouthwash containing ClO2 is
effective against halitosis in the capacity of lowering the levels of the VSC components, namely, H2S, CH3SH, and (CH3)2S, in
the oral cavity. Unlike in the control group, the test group indicates that gargling with mouthwash containing ClO2 is effective in
reducing halitosis.
A Focus on Chlorine Dioxide: The Promising Food Preservative -- "In conclusion, as a strong oxidizing agent,
ClO2 has the potential tobe an alternative to Cl2 to maintain the postharvest storage quality and enhance the microbiological
safety of foods, without posing any healthrisks to consumers."
Chlorine Dioxide Is a Size-Selective Antimicrobial Agent.
Conclusion: "Chlorine dioxide is a size selective antimicrobial agent which can kill micron sized organisms rapidly,
but cannot make real harm to much larger organisms like animals or humans as it is not able to penetrate deeply into their
living tissues. Moreover, the circulation of multicellular organisms can provide an additional protection to these organisms
against ClO2."
The Universal Antidote: The Science & Story Behind Chlorine Dioxide --
Interactive Reference Guidebook> -- (PDF booklet, 79 pages).