Heavy Metal Exposure:
The Dangers Can Be
Significant If Left
Heavy metals are naturally occurring elements that have a high atomic weight and a density at least five (5) times greater than that of water. Their multiple industrial, domestic, agricultural, medical and technological applications have led to their wide distribution in the environment; raising concerns over their potential effects on human health and the environment. Their toxicity depends on several factors including the dose, route of exposure, and chemical species, as well as the age, gender, genetics, and nutritional status of exposed individuals. Because of their high degree of toxicity, arsenic, cadmium, lead, and mercury rank among the priority metals that are of public health significance. These metallic elements are considered systemic toxicants that are known to induce multiple organ damage, even at lower levels of exposure. They are also classified as human carcinogens (known or probable) according to the U.S. Environmental Protection Agency, and the International Agency for Research on Cancer.
Source: Heavy Metals Toxicity and the Environment, Paul B Tchounwou,* Clement G Yedjou, Anita K Patlolla, and Dwayne J Sutton EXS. 2012; 101: 133–164. doi: 10.1007/978-3-7643-8340-4_6 PMCID: PMC4144270 NIHMSID: NIHMS414261
Heavy metal toxicity damages: Central nervous system, Cardiovascular system, Gastrointestinal system, Lungs, Kidneys, Liver, Endocrine glands, Bones; Jang 2011; Adal 2013.
Chronic heavy metal exposure has been implicated in several degenerative diseases of these same systems and may increase the risk of some cancers.
Galanis 2009; Wu 2012.
Even people who are not occupationally exposed carry certain metals in their body as a result of exposure from other sources, such as food, beverages, or air.
Washam 2011; Satarug 2010.
Chronic toxicities are manifested as conditions that develop over extended periods from chronic exposure to relatively low concentrations (e.g., sustained environmental exposure). Symptoms of chronic heavy metal toxicity can be similar to other health conditions and may not be immediately recognized as intoxications. Increased cancer risk is a common feature of chronic exposure to certain metals; the exact mechanism of their carcinogenicity is not completely understood, although many are weak mutagens (cause DNA damage), can disrupt gene expression, and deregulate cell growth and development.
They can also interfere with innate DNA repair systems.
In addition, certain metals may affect gene expression and alter gene function.
Arita 2009; Martinez-Zamudio 2011.
"More than 125 million Americans live in counties with unhealthy levels of air pollution, according to the American Lung Association's 2017 "State of the Air" report. Pollution leads to various kinds of nasty health outcomes, including asthma, lung cancer, and shortened lifespans."
Business Insider, April 20, 2017
"Americans make up an estimated 5% of the world's population. However, the US uses 25% of the world's resources -- burning up nearly 25% of the coal, 26% of the oil, and 27% of the world's natural gas. Each year 1.2 trillion gallons of untreated sewage, stormwater, and industrial waste are dumped into U.S. water. Across Europe, dangerous wastes have been dumped on to the soil for decades without consideration of the long-term problems. The same story can be seen in commercial and industrial sites, where hazardous chemicals were regularly used, spilt, lost, and discarded. In the WHO European Region alone, exposure to particulate matter (PM) decreases the life expectancy of every person by an average of almost 1 year, mostly due to increased risk of cardiovascular and respiratory diseases and lung cancer."
Heavy metal removal / detoxification
Background: Clear (tm) is a powerful new product created to support the body's efforts to eliminate harmful heavy metals and other toxins. Clear delivers a proprietary blend of proven ingredients for chelation and detoxification past the harsh environment of the stomach via liposomal encapsulation to be absorbed in the small intestine and put immediately to use. Each of the key ingredients; EDTA, Glutathione, N-Acetyl Cysteine, R-Alpha Lipoic Acid, Huperzine A, Vitamin B2, and Niacin are beneficial as a stand-alone supplement and work even more powerfully together in this proprietary formulation to support elimination of dangerous toxins.
The recommended 4 sprays each in the morning and the evening provides:
EDTA: Ethylenediaminetetraacetic Acid (EDTA) is a molecule that, because of its claw-like shape and affinity for heavy metals, operates in the body as a chelating agent to capture these toxins and hold them in a form that the body can eliminate.Glutathione: Glutathione - GSH is the cell’s predominant molecule for detoxification, performing critical transformation of reactive oxygen species - ROS, and is important to deliver as part of the chelation "package." GSH also maintains exogenous antioxidants such as vitamins C and E in their reduced (active) forms. It also regulates the critical nitric oxide cycle. It is used in metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation. Thus, every system in the body can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system, and the lungs. It has a vital function in iron metabolism. It has roles in progression of the cell cycle, including cell death. GSH levels regulate redox changes to nuclear proteins necessary for the initiation of cell differentiation.
The U.S. Food and Drug Administration (FDA) approved EDTA chelation therapy as a treatment for lead and heavy metal poisoning with an I.V. delivery protocol - due to poor oral absorption.
N-Acetyl Cysteine: N-Acetyl Cysteine - NAC is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. NAC is a slightly modified version of the sulfur-containing amino acid cysteine. When taken internally, NAC replenishes intracellular levels of the natural antioxidant glutathione (GSH), helping to restore cells’ ability to fight damage from reactive oxygen species (ROS).
NAC also performs a critical protective role in the prevention of many common diseases due to regulation of gene expression in pathways linking oxidative stress to inflammation. It provides significant neuro-protective functions and is being used therapeutically and studied for Alzheimer’s Disease, bipolar disorder, obsessive-compulsive disorder, schizophrenia, cocaine addiction, and in progressive myoclonic epilepsy.
R-alpha Lipoic Acid: R-alpha Lipoic Acid - RLA is a potent anti-oxidant, a powerful chelator, and a physio- and neuro-protector. This multifunctional agent works to chelate the dangerous metals and metalloids arsenic, cadmium, lead, and mercury so they can be safely excreted from the body.
RLA is essential to aerobic metabolism and promotes optimal blood sugar levels and insulin sensitivity.
It can act in both water-soluble and fat-soluble domains, and is able to cross the blood-brain barrier to provide neuro-protective functions.
RLA teams with B vitamins to support energy production and helps protect mitochondria.
Huperzine A: Huperzine A - an extract from the club moss Huperzia Serrata. The whole moss plant has been used in Traditional Chinese Medicine as far back as the Tang Dynasty, known variously as Chien Tseng Ta, Jin Bu Buan, Qian Ceng Ta, She Zu Cao, Shi Song. The extracted alkaloid is a potent acetylcholinesterase (AChE) inhibitor, making more acetylcholine available for use in the brain and nervous system. One of the many negative effects of heavy metal toxicity is the disruption of acetylcholine effectiveness.
HupA also protects against and improves function after exposure to organophosphates in insecticides and herbicides.
Vitamin B2: Vitamin B2 - Riboflavin is responsible for maintaining healthy blood cells, helping to boost energy levels, facilitating a healthy metabolism, preventing free radical damage, contributing to growth, protecting skin and eye health.
B2 boosts energy, increases blood circulation, regulates thyroid activity, is neuro-protective, protects vision, prevents HIV/AIDS, boosts mineral absorption, repairs tissue, protects GI tract, and promotes healthy fetal development.
Niacin: Niacin - B3 (along with nicotinamide) is an essential human nutrient and is a precursor to both NAD and NADP.
NAD is important in catabolism of fat, carbohydrate, protein, and alcohol, as well as cell signaling and DNA repair, and NADP in anabolism reactions such as fatty acid and cholesterol synthesis.
The high energy requirements of the brain and the high turnover rate of the GI tract tissues and skin are particularly susceptible to deficiencies.